NOF Clinician's Guide to Prevention and Treatment of Osteoporosis
This useful guide is a must for informing clinical decision-making for the management of men and women at high fracture risk. It integrates the expression of a patient's fracture risk as a 10-year probability (the output from FRAX®) with current clinical recommendations for the management of osteoporosis.
According to the Clinician's Guide, healthcare providers should consider FDA-approved medical therapies in postmenopausal women and men aged 50 years and older, based on the following:
- A hip or vertebral (clinical or morphometric) fracture
- T-score ≤ -2.5 at the femoral neck or spine after appropriate evaluation to exclude secondary causes
- Low bone mass (T-score between -1.0 and -2.5 at the femoral neck or spine) AND a 10-year probability of a hip fracture ≥ 3% OR a 10-year probability of a major osteoporosis-related fracture ≥ 20% based on the US-adapted WHO algorithm
- Clinician's judgment and/or patient preferences may indicate treatment for people with 10-year fracture probabilities above or below these levels
The Clinician's Guide is available as a downloadable document (updated in 2010)
